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Last Updated: March 29, 2024

Details for Patent: 7,229,644


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Title:Pharmaceutical formulations of modafinil
Abstract: The present invention is related to compositions of modafinil, including compositions of modafinil and one or more diluents, disintegrants, binders and lubricants, and the processes for their preparation thereof.
Inventor(s): Corvari; Vincent (Carmel, IN), Grandolfi; George (Milford, OH), Parikh; Alpa (Hockessin, DE)
Assignee: Cephalon, Inc. (Frazer, PA)
Filing Date:Sep 13, 2002
Application Number:10/243,557
Claims:1. A composition comprising modafinil, wherein modafinil comprises about 90% by weight of the composition; a lactose monohydrate, which comprises about 3-10% of the composition by weight; a cross-linked sodium carboxymethyl cellulose, which comprises about 2-5% of the composition by weight; a polyvinyl pyrrolidone, which comprises about 2-5% of the composition by weight; and magnesium stearate, which comprises about 0.2-2.0% of the composition by weight.

2. The composition of claim 1, wherein modafinil is the levorotatory isomer of modafinil.

3. A composition comprising modafinil, wherein modafinil comprises 70-80% of the composition by weight; a lactose monohydrate from about 3-20% of the composition by weight; a cross-linked sodium carboxymethyl cellulose from about 2-10% of the composition by weight; a polyvinyl pyrrolidone from about 2-10% of the composition by weight, and magnesium stearate from about 0.2-2.0% of the composition by weight.

4. The composition of claim 3, wherein modafinil is the levorotatory isomer of modafinil.

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