Details for Patent: 7,189,854
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Title: | Cyclic protein tyrosine kinase inhibitors |
Abstract: | Novel cyclic compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of protein tyrosine kinase-associated disorders such as immunologic and oncologic disorders. |
Inventor(s): | Das; Jagabandhu (Mercerville, NJ), Chen; Ping (Belle Mead, NJ), Norris; Derek J. (Trenton, NJ) |
Assignee: | Bristol-Myers Squibb Company (Princeton, NJ) |
Filing Date: | May 26, 2005 |
Application Number: | 11/138,793 |
Claims: | 1. A process for preparing a compound having formula (A), ##STR00622## comprising reacting a compound having formula (B), ##STR00623## with a compound of formula (C), ##STR00624## to provide the compound of formula (A). 2. The process of claim 1, wherein reacting the compound of formula (B) with the compound of formula (C) comprises mixing the compound of formula (B) with the compound of formula (C) and heating. 3. The process of claim 1, further comprising preparing the compound of the formula (B), by reacting the compound of formula (D) ##STR00625## with the compound of formula (E) ##STR00626## to provide the compound of formula (B). 4. The process of claim 3, wherein reacting the compound of formula (D) with the compound of formula (E) comprises adding base. 5. A process for preparing a compound having formula (B), ##STR00627## comprising reacting the compound of formula (D) ##STR00628## with the compound of formula (E) ##STR00629## to provide the compound of formula (B). 6. The process of claim 5, wherein reacting the compound of formula (D) with the compound of formula (E) comprises adding base. 7. The compound of formula (D) ##STR00630## or salt thereof. 8. The compound of formula (B) ##STR00631## or salt thereof. |