Details for Patent: 7,153,948
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Title: | High-affinity oligonucleotide ligands to vascular endothelial growth factor (VEGF) |
Abstract: | Methods are described for the identification and preparation of nucleic acid ligand ligands to vascular endothelial growth factor (VEGF). Included in the invention are specific RNA ligands to VEGF identified by the SELEX method. |
Inventor(s): | Gold; Larry (Boulder, CO), Janjic; Nebojsa (Boulder, CO) |
Assignee: | Gilead Sciences, Inc. (Foster City, CA) |
Filing Date: | Apr 07, 2003 |
Application Number: | 10/409,565 |
Claims: | 1. RNA ligand to VEGF comprising the sequence: ##STR00001## wherein: V is A, C, or G; N is any base; and prime (') indicates a complementary base. |