Make Better Decisions

  • Analyze global market entry opportunities
  • Uncover prior art in expired and abandoned patents
  • Drug patents in 130+ countries

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving leading biopharmaceutical companies globally:

Farmers Insurance
Express Scripts
US Department of Justice
Johnson and Johnson

Generated: January 19, 2018

DrugPatentWatch Database Preview

Details for Patent: ➤ Subscribe

« Back to Dashboard

Details for Patent: ➤ Subscribe

Title:Intermediates for N-substituted carbamoyloxyalkyl-azolium derivatives
Abstract: N-substituted carbamoyloxyalkyl-azolium derivatives which have antifungal activity and are useful for the treatment of fungal diseases.
Inventor(s): Fukuda; Hiroshi (Tokyo, JP), Hayase; Tadakatsu (Chigasaki, JP), Mizuguchi; Eisaku (Kamakura, JP), Shimma; Nobuo (Chigasaki, JP), Ohwada; Jun (Kamakura, JP), Oikawa; Nobuhiro (Kawasaki, JP), Sakaitani; Masahiro (Chigasaki, JP), Tsukazaki; Masao (Fujisawa, JP), Umeda; Isao (Yokohama, JP)
Assignee: Basilea Pharmaceutica AG (CH)
Filing Date:Sep 03, 2004
Application Number:10/934,551
Claims:1. The compound having the formula: ##STR00037## wherein R.sup.1 is hydrogen or alkyl; R.sup.2 is hydrogen, alkyl, alkylcarbonyloxyalkyl, alkoxycarbonyl, alkylcarbonyl, mono- or dialkylaminoalkylcarbonyloxyalkyl; group ##STR00038## is pyridin-2-yl; L is a chloro, bromo, iodo, tosyloxy or mesyloxy; R.sup.4 and R.sup.5 are independently selected from the group consisting of hydrogen, halogen, alkyl, alkoxy, alkylthio, alkylsulfinyl, alkylsulfonyl, carboxy, alkyloxycarbonyl, cyano, trifluoromethyl, trifluoromethoxy, nitro, aminosulfonyl, alkylaminocarbonyloxyalkyl, and sulfo, R.sup.4 and R.sup.5 are in addition alkylcarbonyloxyalkyl or aminoalkylcarbonyloxyalkyl and R.sup.6 is hydroxy, alkoxycarbonylalkylamino, alkoxycarbonylamino, amino, alkylamino, alkylcarbonyloxy, alkoxycarbonylalkylaminoalkylcarbonyloxy, alkoxycarbonylaminoalkylcarbonyloxy, alkylaminoalkylcarbonyloxy, aminoalkylcarbonyloxy, alkylcarbonylamino, alkylcarbonylalkylamino, acyloxy, acylamino, or acylalkylamino.

2. The compound of claim 1 wherein the pyridin-2-yl group is substituted with alkylaminoalkylcarbonyloxyalkyl, alkylcarbonyloxyalkyl, or aminoalkylcarbonyloxyalkyl.

3. The compound of claim 1 wherein R.sup.4 and R.sup.5 are independently selected from the group consisting of hydrogen, halogen, alkoxy, cyano, trifluoromethyl, trifluormethoxy and nitro.

4. The compound of claim 3 wherein R.sup.4 and R.sup.5 are independently selected from the group consisting of hydrogen, halogen and alkoxy.

5. The compound of claim 4 wherein R.sup.4 and R.sup.5 are hydrogen.

6. The compound of claim 1 wherein R.sup.6 is alkylamino, alkylcarbonyloxy, alkylaminoalkylcarbonyloxy or aminoalkylcarbonyloxy.

7. The compound of claim 6 wherein R.sup.6 is alkylaminoalkylcarbonyloxy.

8. The compound of claim 4 wherein said compound is [N-methyl-N-3-((tert-butoxycarbonylmethylamino) acetoxymethl)pyridin-2-yl]carbamic acid 1-chloro-ethyl ester.

9. The compound of claim 4 wherein said compound is [N-methyl-N-3-(acetoxymethyl)pyridin-2-yl]carbamic acid 1-chloro ethyl ester.

10. The compound of claim 4 wherein said compound is [N-methyl-N-3-[(tert-butoxycarbonylamino)acetoxymethyl)pyridin-2-yl]carba- mic acid 1-chloro ethyl ester.
« Back to Dashboard

For more information try a trial or see the plans and pricing

Serving leading biopharmaceutical companies globally:

Harvard Business School
Chinese Patent Office
Federal Trade Commission
US Department of Justice

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

Copyright 2002-2018 thinkBiotech LLC
ISSN: 2162-2639

Secure SSL Encrypted
Privacy and Cookies
Terms & Conditions

Follow DrugPatentWatch: