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Details for Patent: 7,131,441

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Details for Patent: 7,131,441

Title:Inhaler for multiple dosed administration of a pharmacological dry powder
Abstract: An inhaler for multiple dosed administration of a pharmacological dry powder has a housing with a mouthpiece fitted thereon and a removable protective cap that covers the mouthpiece prior to removal. The mouthpiece may be fitted with or without lip grooves, which aid a user in the positioning and manipulation of the inhaler. The inhaler includes a dosing slide, a carriage, a dosing cavity and a valve shield, all of which are arranged within the housing. Removal of the protective cap initiates dosing, which consists of a dose of a pharmacological dry powder being received in the dosing cavity and then transported to the mouthpiece by means of the dosing slide. Only upon application of a defined minimum intensity of inhalation is the shutter moved by the suctioned valve shield, resulting in the release of the dose for inhalation.
Inventor(s): Keller; Manfred (Bad Krozingen, DE), Eggimann; Thomas (Pratteln, CH)
Assignee: SkyePharma AG (Muttenz, CH)
Filing Date:May 12, 2000
Application Number:09/570,107
Claims:1. A mouthpiece for an inhaler, comprising: a channel inlet; a mouth tube having a channel outlet; and an atomizer path extending within said mouth tube from said channel inlet to said channel outlet, said atomizer path including a first channel section having at least one baffle and a second channel section in communication with said first channel section, said second channel section having a larger volume than said first channel section, said mouth tube including a curved exterior surface having a top side and a bottom side; and a pair of lip grooves that are sized and shaped so as to receive the lips of a patient and that are arranged on said curved exterior surface such that one lip groove is located on said top side and the other lip groove is located opposite said first groove on said bottom side, said mouth tube being comprised of a pair of symmetrical halves, each having corresponding complementary connecting elements and being connected to one another by an integral hinge, one of said symmetrical halves having a first groove segment and a second groove segment, and the other of said symmetrical halves having a third groove segment and a fourth groove segment, said third groove segment cooperating with said first groove segment to form said one lip groove, and said fourth groove segment cooperating with said second groove segment to form said other lip groove.

2. The mouthpiece according to claim 1, wherein said mouthpiece is adapted for use with an inhaler for administration of pharmacological dry powder.

3. The mouthpiece according to claim 1, wherein said first channel section of said atomizer path is formed by walls and said walls form said at least one baffle.

4. The mouthpiece according to claim 3, wherein said first channel section includes a plurality of baffles which protrude into said atomizer path, thereby forming a plurality of curves within said atomizer path.

5. The mouthpiece according to claim 4, further comprising a ramp which is positioned at the channel inlet.

6. A mouthpiece for an inhaler, comprising: a mouth tube having an end face with an upper portion and a channel outlet located in said upper portion of said end face, said mouth tube including a curved exterior surface having a top side and a bottom side; and a pair of lip grooves that are sized and shaped so as to receive the lips of a patient and that are arranged on said curved exterior surface such that one lip groove is located on said top side and the other lip groove is located opposite said first groove on said bottom side; wherein said mouth tube is further comprised of a pair of symmetrical halves, each having corresponding complementary connecting elements, wherein said symmetrical halves of said mouth tube are connected to one another by an integral hinge; and wherein one of said symmetrical halves has a first groove segment and a second groove segment, and the other of said symmetrical halves has a third groove segment and a fourth groove segment, said third groove segment cooperating with said first groove segment to form said one lip groove, and said fourth groove segment cooperating with said second groove segment to form said other lip groove; and an atomizer path extending within said mouth tube from said channel inlet to said channel outlet, said atomizer path including a first channel section and a second channel section, said first channel section having at least one baffle and being in communication with said channel inlet and located at a first level, said second channel section being in communication with said first channel section and said channel outlet; said second channel section including a first portion located at said first level, said first portion communicating with said first channel section and having a larger volume than said first channel section, and a second portion located at a second level which is higher than the first level, said second portion being in communication with said channel outlet of said mouth tube; and said channel outlet including a horizontally oriented slit located in said upper portion of said end face of said mouth tube.

7. The mouthpiece according to claim 6, wherein said mouthpiece is adapted for use with an inhaler for administration of pharmacological dry powder.

8. The mouthpiece according to claim 6, wherein said first channel section of said atomizer path is formed by walls and said walls form said at least one baffle.

9. The mouthpiece according to claim 8, wherein said first channel section includes a plurality of baffles which protrude into said atomizer path, thereby forming a plurality of curves within said atomizer path.

10. The mouthpiece according to claim 9, further comprising a ramp which is positioned at the channel inlet.
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