Details for Patent: 7,070,805
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Title: | Rapidly disintegrable solid preparation |
Abstract: | A rapidly disintegrable solid preparation which comprises (i) a pharmacologically active ingredient, (ii) a sugar and (iii) a low-substituted hydroxypropylcellulose having 5% by weight or more to less than 7% by weight of hydroxypropoxyl group. The rapidly disintegrable solid preparation has fast disintegrability, suitable strength and no roughness. |
Inventor(s): | Shimizu; Toshihiro (Itami, JP), Sugaya; Masae (Ikeda, JP), Nakano; Yoshinori (Takarazuka, JP) |
Assignee: | Takeda Pharmaceutical Company Limited (Osaka, JP) |
Filing Date: | Mar 07, 2001 |
Application Number: | 09/800,839 |
Claims: | 1. An oral rapidly disintegrable solid preparation which comprises (i) manidipine hydrochloride, (ii) a sugar and (iii) a low-substituted hydroxypropylcellulose having 5% by weight or more to less than 7% by weight of hydroxypropoxyl groups; wherein said solid preparation is buccally dissolved in from about 5 to about 50 seconds. 2. An oral rapidly disintegrable solid preparation which comprises (i) pioglitazone hydrochloride, (ii) a sugar and (iii) a low-substituted hydroxypropylcellulose having 5% by weight or more to less than 7% by weight of hydroxypropoxyl groups; wherein said solid preparation is buccally dissolved in from about 5 to about 50 seconds. |