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Generated: February 17, 2018

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Title:Rapidly disintegrable solid preparation
Abstract: A rapidly disintegrable solid preparation which comprises (i) a pharmacologically active ingredient, (ii) a sugar and (iii) a low-substituted hydroxypropylcellulose having 5% by weight or more to less than 7% by weight of hydroxypropoxyl group. The rapidly disintegrable solid preparation has fast disintegrability, suitable strength and no roughness.
Inventor(s): Shimizu; Toshihiro (Itami, JP), Sugaya; Masae (Ikeda, JP), Nakano; Yoshinori (Takarazuka, JP)
Assignee: Takeda Pharmaceutical Company Limited (Osaka, JP)
Filing Date:Mar 07, 2001
Application Number:09/800,839
Claims:1. An oral rapidly disintegrable solid preparation which comprises (i) manidipine hydrochloride, (ii) a sugar and (iii) a low-substituted hydroxypropylcellulose having 5% by weight or more to less than 7% by weight of hydroxypropoxyl groups; wherein said solid preparation is buccally dissolved in from about 5 to about 50 seconds.

2. An oral rapidly disintegrable solid preparation which comprises (i) pioglitazone hydrochloride, (ii) a sugar and (iii) a low-substituted hydroxypropylcellulose having 5% by weight or more to less than 7% by weight of hydroxypropoxyl groups; wherein said solid preparation is buccally dissolved in from about 5 to about 50 seconds.
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Queensland Health
Johnson and Johnson
Medtronic
McKesson
Novartis
Julphar
Dow
Farmers Insurance
Moodys
Harvard Business School

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