Details for Patent: 6,992,108
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Title: | Means for the modulation of processes mediated by retinoid receptors and compounds useful therefor |
Abstract: | A method for modulating lipid metabolism in a subject by administering 9-cis retinoic acid is presented. The 9-cis retinoic acid is more specific for the retinoid X receptor than is retinoic acid. |
Inventor(s): | Evans; Ronald M. (La Jolla, CA), Mangelsdorf; David J. (Dallas, TX), Heyman; Richard A. (Encinitas, CA), Boehm; Marcus F. (San Diego, CA), Eichele; Gregor (Houston, TX), Thaller; Christina (Houston, TX) |
Assignee: | The Salk Institute for Biological Studies (La Jolla, CA) Baylor College of Medicine (Houston, TX) Ligand Pharmaceuticals, Inc. (San Diego, CA) |
Filing Date: | Jun 07, 1995 |
Application Number: | 08/482,737 |
Claims: | 1. A method to modulate lipid metabolism in a subject, said method comprising administering to said subject an effective amount of 9-cis-retinoic acid, or pharmaceutically acceptable carrier containing same. |