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Last Updated: April 19, 2024

Details for Patent: 6,992,108


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Title:Means for the modulation of processes mediated by retinoid receptors and compounds useful therefor
Abstract: A method for modulating lipid metabolism in a subject by administering 9-cis retinoic acid is presented. The 9-cis retinoic acid is more specific for the retinoid X receptor than is retinoic acid.
Inventor(s): Evans; Ronald M. (La Jolla, CA), Mangelsdorf; David J. (Dallas, TX), Heyman; Richard A. (Encinitas, CA), Boehm; Marcus F. (San Diego, CA), Eichele; Gregor (Houston, TX), Thaller; Christina (Houston, TX)
Assignee: The Salk Institute for Biological Studies (La Jolla, CA) Baylor College of Medicine (Houston, TX) Ligand Pharmaceuticals, Inc. (San Diego, CA)
Filing Date:Jun 07, 1995
Application Number:08/482,737
Claims:1. A method to modulate lipid metabolism in a subject, said method comprising administering to said subject an effective amount of 9-cis-retinoic acid, or pharmaceutically acceptable carrier containing same.

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