.

Pharmaceutical Business Intelligence

  • Anticipate P&T budget requirements
  • Evaluate market entry opportunities
  • Find generic sources and suppliers
  • Predict branded drug patent expiration

► Plans and Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

DrugPatentWatch Database Preview

Details for Patent: 6,919,320

« Back to Dashboard

Details for Patent: 6,919,320

Title: Pharmaceutical compositions containing deoxyribonucleosides for wound healing
Abstract:The invention relates to compositions comprising 2'-deoxyribonucleosides. The invention also relates to methods of accelerating the healing of wounds, abrasions, cuts, incisions, and superficial burns induced by heat, sunlight, chemical agents, or infections, and methods for ameliorating the effects of aging of the epidermal tissues comprising administering the compositions of the present invention to an animal.
Inventor(s): von Borstel; Reid Warren (Kensington, MD), Bamat; Michael Kevin (Chevy Chase, MD)
Assignee: Wellstat Therapeutics Corporation (Gaithersburg, MD)
Filing Date:Jun 07, 1995
Application Number:08/473,331
Claims:1. A composition of matter in the form of a lotion, ointment, cream or gel, comprising, an active agent comprising (a) from 10 to 90 percent by mol 2'-deoxycytidine, and (b) from 90 to 10 percent by mol 2'-deoxyguanosine, or the pharmaceutically acceptable salts thereof, and a pharmaceutically acceptable carrier; wherein said active agent is present at a concentration such that said composition is capable of promoting wound healing in an animal, and wherein said carrier is adapted for local or topical administration.

2. A composition of matter as recited in claim 1 wherein each of said components is present in from 25 to 75 percent of said composition.

3. A composition of matter in the form of a lotion, ointment, cream or gel, consisting essentially of, an active agent comprising (a) from 10 to 90 percent by mol 2'-deoxycytidine, and (b) from 90 to 10 percent by mol 2'-deoxyguanosine, or the pharmaceutically acceptable salts thereof, and a pharmaceutically acceptable carrier; wherein said active agent is present at a concentration such that said composition is capable of promoting wound healing in an animal, and wherein said carrier is adapted for local or topical administration.

4. A composition of matter in the form of a lotion, ointment, cream or gel, comprising, an active agent comprising (a) from 10 to 90 percent by mol 2'-deoxycytidine, and (b) from 90 to 10 percent by mol 2'-deoxyguanosine, each of said 2'-deoxycytidine and 2'-deoxyguanosine being present as (i) the free from thereof, or (ii) a substituted derivative of (a) or (b), wherein one or both of said 2'-deoxycytidine and 2'-deoxyguanosine are substituted by one or more groups which may be the same or different, at one or both hydroxyl groups in the deoxyribose moiety and/or substituted in the exocyclic amine on the purine ring of 2'-deoxyguanosine or in the exocyclic amine on the pyrimidine ring of 2'-deoxycytidine by an acyl radicals containing 2 to 20 carbon atoms, or the pharmaceutically acceptable salts thereof, and a pharmaceutically acceptable carrier; wherein said active agent is present at a concentration such that said composition is capable of promoting wound healing in an animal, and wherein said carrier is adapted for local or topical administration.

5. A composition as in claim 1 further comprising 2'-deoxyadenosine.

6. A composition as in claim 1 further comprising 2'-deoxythymidine.

7. A composition as in claim 5 further comprising 2'-deoxythymidine.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

`abc