|Title:||Immunoassays for human brain natriuretic peptide|
|Abstract:||Immunoassays and antibodies useful in conducting them for human and canine brain natriuretic peptide are described.|
|Inventor(s):||Seilhamer; J. Jeffrey (Milpitas, CA), Lewicki; John (San Jose, CA), Scarborough; Robert M. (Hayward, CA), Porter; J. Gordon (Newark, CA)|
|Assignee:||Scios, Inc. (Fremont, CA)|
|Filing Date:||Jul 09, 2001|
|Claims:||1. Isolated antibodies useful for immunoassays to detect and which specifically bind human brain natriuretic peptide of the formula: |
2. The antibodies of claim 1 which are monoclonal antibodies.
3. The antibodies of claim 1 which further comprise a label.
4. A method to perform an immunoassay to detect human brain natriuretic peptide in a sample which method comprises contacting said sample with the antibodies of claim 1 and assessing the ability of said antibodies to immunoreact with any human brain natriuretic peptide contained in said sample.
5. A kit for conducting an immunoassay to detect human brain natriuretic peptide which kit comprises the antibodies of claim 1 in containers and reagents capable of recognizing and specifically binding to said peptide or said antibodies in additional containers.