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Last Updated: April 24, 2024

Details for Patent: 6,872,838


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Title: Water soluble prodrugs of hindered alcohols
Abstract:The present invention is directed to novel water-soluble prodrugs of aliphatic or aromatic hindered hydroxyl group containing pharmaceuticals.
Inventor(s): Stella; Valentino J. (Lawrence, KS), Zygmunt; Jan J. (Longmont, CO), Georg; Ingrid Gunda (Lawrence, KS), Safadi; Muhammad S. (Nazareth, IL)
Assignee: University of Kansas (Lawrence, KS)
Filing Date:Jul 29, 2002
Application Number:10/208,647
Claims:1. A compound selected from the group consisting of O-phosphonoxymethylpropofol Dibenzy ester, O-phosphonoxymethyl-alpha-tocopherol Dibenzyl ester, and 4'-O-phosphonooxymethyletopside Dibenzyl ester.

2. A compound selected from the group consisting of O-phosphonoxymethylpropofol Disodium salt, O-phosphonoxymethyl-alpha-tocopherol Disodium salt, and 4'-O-phosphonoxymethyletoposide Disodium salt.

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