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Generated: December 16, 2017

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Title: Methods for treating irritable bowel syndrome
Abstract:This invention relates to the use of 5-HT3 receptor antagonists in the treatment of nonconstipated female IBS patients.
Inventor(s): Mangel; Allen Wayne (Chapel Hill, NC), Northcutt; Allison Ruth (Raleigh, NC)
Assignee: SmithKline Beecham Corporation (Philadelphia, PA)
Filing Date:Jun 10, 2002
Application Number:10/166,401
Claims:1. A method for improving bowel movement frequency in non-constipated female IBS which comprises administering an effective amount of a 5-HT.sub.3 receptor antagonist or a pharmaceutically acceptable derivative thereof.

2. The method according to claim 1, wherein the 5-HT.sub.3 receptor antagonist is alosetron or a pharmaceutically acceptable derivative thereof.

3. The method according to claim 2, wherein alosetron is in the form of its hydrochloride.

4. The method according to claim 1, wherein the 5-HT.sub.3 receptor antagonist is selected from granisetron, azasetron, tropisetron, ramosetron, ondansetron, lerisetron, (R) zacopride, cilansetron, itasetron, indisetron and dolasetron.
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