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Details for Patent: 6,569,883

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Details for Patent: 6,569,883

Title: Medicaments
Abstract:The invention relates to the use of compounds of the general formula (I) ##STR1## wherein R.sup.1 represents a hydrogen atom or a C.sub.1-10 alkyl, C.sub.3-7 cycloalkyl, C.sub.3-7 cycloalkyl-(C.sub.1-4)alkyl, C.sub.3-6 alkenyl, C.sub.3-10 alkynyl, phenyl or phenyl-C.sub.1-3 alkyl group; and one of the groups represented by R.sup.2, R.sup.3 and R.sup.4 is a hydrogen atom or a C.sub.1-6 alkyl, C.sub.3-7 cycloalkyl, C.sub.2-6 alkenyl or phenyl-C.sub.1-3 alkyl group and each of the other two groups, which may be the same or different, represents a hydrogen atom or a C.sub.1-6 alkyl group; and physiologically acceptable salts and solvates thereof, for the relief of nausea and vomiting and/or the promotion of gastric emptying and for the manufacture of a medicament for this purpose.
Inventor(s): Tyers; Michael Brian (Welwyn, GB), Coates; Ian Harold (Hertford, GB), Humber; David Cedric (London, GB), Ewan; George Blanch (Gerrards Cross, GB), Bell; James Angus (Royston, GB)
Assignee: Glaxo Group Limited (Greenford, GB)
Filing Date:May 05, 1999
Application Number:09/305,194
Claims:1. A pharmaceutical composition comprising an effective amount of R-1,2,3,9-tetrahydro-3-[(2-methyl-1H-imidazol-1-yl)methyl]-9-methyl-4H-car bazol-4-one hydrochloride dihydrate adapted for rectal administration.
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