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Serving hundreds of leading biopharmaceutical companies globally:

Fish and Richardson
Farmers Insurance
Baxter
UBS
Cipla
Mallinckrodt
Boehringer Ingelheim
Merck
Chinese Patent Office

Generated: May 22, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,525,096

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Title: GABA and L-glutamic acid analogs for antiseizure treatment
Abstract:A compound of the formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R.sub.2 is hydrogen or methyl; and R.sub.3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.
Inventor(s): Silverman; Richard B. (Morton Grove, IL), Andruszkiewicz; Ryszard (Sopot, PL), Yuen; Po-Wai (Ann Arbor, MI), Sobieray; Denis Martin (Holland, MI), Franklin; Lloyd Charles (Hamilton, MI), Schwindt; Mark Alan (Holland, MI)
Assignee: Northwestern University (Evanston, IL) Warner-Lambert Company (Ann Arbor, MI)
Filing Date:Feb 04, 1999
Application Number:09/244,313
Claims:1. A method of treating a patient having Parkinson's Disease which includes administering to a patient an anti-seizure effective amount of the compound 4-amino-3-(2-methylpropyl) butanolc acid.

2. A method of treating a patient having Parkinson's Disease which includes administering to a patient an anti-seizure effective amount of the compound S-(+)-4-amino-3-(2-methylpropyl)butanoic acid.

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Serving hundreds of leading biopharmaceutical companies globally:

McKinsey
UBS
Colorcon
Healthtrust
Julphar
Queensland Health
Accenture
QuintilesIMS
Daiichi Sankyo

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