Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving hundreds of leading biopharmaceutical companies globally:

Cerilliant
Fuji
Medtronic
Teva
Healthtrust
Daiichi Sankyo
QuintilesIMS
Mallinckrodt
US Department of Justice

Generated: April 21, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,479,673

« Back to Dashboard

Title: Antiretroviral enantiomeric nucleotide analogs
Abstract:Resolved enantiomers of the formula ##STR1## wherein B is a purine or pyrimidine base or aza and/or deaza analogs thereof are useful in antiviral pharmaceutical compositions to treat retroviral infections.
Inventor(s): Holy; Antonin (Prague, CZ), Dvorakova; Hana (Prague, CZ), DeClercq; Erik Desire Alice (Lovenjoel, BE), Balzarini; Jan Marie Rene (Heverlee, BE)
Assignee: Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic (CZ) N/A (BE) Rega Stichting, V.Z.W. (N/A)
Filing Date:Feb 08, 2000
Application Number:09/500,148
Claims:1. A compound of the formula: ##STR13##

as the enriched or resolved (S) enantiomer.

2. A compound of the formula: ##STR14##

wherein LvO is a leaving group, as a racemate or as the enriched or resolved enantiomers.

3. The compound of claim 2 wherein Lv is toluenesulfonyl.

4. The compound of claim 2 which is the enriched or resolved (R) enantiomer.

5. The compound of claim 2 which is the enriched or resolved (S) enantiomer.

6. A compound of the formula: ##STR15##

as the enriched or resolved (R)enantiomer.

For more information try a trial or see the plans and pricing

Serving hundreds of leading biopharmaceutical companies globally:

Healthtrust
Johnson and Johnson
Covington
Federal Trade Commission
Fuji
Julphar
Fish and Richardson
Queensland Health
US Department of Justice

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.