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Generated: January 16, 2018

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Title: Enzymatically active recombinant glucocerebrosidase
Abstract:Recombinant active glucocerebrosidase is produced by a eukaryotic cell. Also, a cell includes nucleic acid encoding enzymatically active glucocerebrosidase; also a eukaryotic organism contains such a cell. Also, a method for producing enzymatically active glucocerebrosidase includes steps of introducing glucocerebrosidase-encoding nucleic acid into a eukaryotic cell, causing the cell to express glucocerebrosidase, and purifying the glucocerebrosidase from the cell.
Inventor(s): Rasmussen; James (Boston, MA), Barsomian; Gary (Georgetown, MA), Bergh; Michel (Belmont, MA)
Assignee: Genzyme Corporation (Cambridge, MA)
Filing Date:May 17, 1995
Application Number:08/442,603
Claims:1. A CHO cell comprising nucleic acid encoding enzymatically active human glucocerebrosidase, said cell being transformed with any plasmid selected from the group pGB20, pGB37 and pGB42.
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