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Details for Patent: 6,346,232

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Details for Patent: 6,346,232

Title: Method of forming conductive lines
Abstract:Pharmaceutical solution aerosol formulations comprising beclomethasone 17,21 dipropionate, ethanol, and a propellant selected from the group consisting of 1,1,1,2-tetrafluoroethane, 1,1,1,2,3,3,3-heptafluoropropane, and a mixture thereof.
Inventor(s): Schultz; Robert K. (Shoreview, MN), Schultz; David W. (Falcon Heights, MN)
Assignee: 3M Innovative Properties Company (St. Paul, MN)
Filing Date:Mar 29, 2000
Application Number:09/537,151
Claims:1. A method of preparing a solution aerosol formulation comprising the step of combining a therapeutically effective amount of beclomethasone 17, 21 dipropionate, a propellant selected from the group consisting of 1,1,1,2-tetrafluoroethane, 1,1,1,2,3,3,3-heptafluoropropane, and a mixture thereof, and ethanol in an amount of 2 to 12 percent by weight to solubilize the beclomethasone 17, 21 dipropionate in the propellant.

2. The method of claim 1, wherein said formulation comprises 0.05 to 0.5% by weight beclomethasone 17, 21 dipropionate.

3. The method of claim 1, wherein said propellant is present in an amount of 88 to 98 percent by weight.

4. The method of claim 1, wherein said formulation comprises 1,1,1,2-tetrafluoroethane as the only propellant.

5. The method of claim 1, wherein said formulation comprises 1,1,1,2,3,3,3-heptafluoropropane as the only propellant.

6. The method of claim 1, wherein said formulation is free of surfactant.

7. The method of claim 1, wherein said formulation consists essentially of a therapeutically effective amount of beclomethasone 17, 21 dipropionate, a propellant selected from the group consisting of 1,1,1,2-tetrafluoroethane, 1,1,1,2,3,3,3-heptafluoropropane, and a mixture thereof, and an amount of ethanol 2 to 12 percent by weight to solubilize the beclomethasone 17, 21 dipropionate in the propellant.
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