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Serving 500+ biopharmaceutical companies globally:

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Generated: July 22, 2017

DrugPatentWatch Database Preview

Details for Patent: 6,342,529

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Details for Patent: 6,342,529

Title: GABA and L-glutamic acid analogs for antiseizure treatment
Abstract:A compound of the formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R.sub.2 is hydrogen or methyl; and R.sub.3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.
Inventor(s): Silverman; Richard B. (Morton Grove, IL), Andruszkiewicz; Ryszard (Sopot, PL), Yuen; Po-Wai (Ann Arbor, MI), Sobieray; Denis Martin (Holland, MI), Franklin; Lloyd Charles (Hamilton, MI), Schwindt; Mark Alan (Holland, MI)
Assignee: Northwestern University (Evanston, IL) Pfizer, Inc. (Ann Arbor, MI)
Filing Date:Feb 04, 1999
Application Number:09/243,946
Claims:1. A method of treating a patient having depression which includes administering to a patient an anti-depressive amount of the compound 4-amino-3-(2-methylpropyl) butanoic acid.

2. A method of treating a patient having depression which includes administering to a patient an anti-depressive amount of the compound S-(+)-4-amino-3-(2-methylpropyl)butanoic acid.
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Serving 500+ biopharmaceutical companies globally:

Teva
Colorcon
McKinsey
US Army
Express Scripts
Cipla
Farmers Insurance
Dow
Healthtrust
Chinese Patent Office

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