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Generated: July 25, 2017
| Title: | Cyclosporin galenic forms |
| Abstract: | Pharmaceutical compositions comprising a cyclosporin as active ingredient, a fatty acid triglyceride, a glycerol fatty acid partial ester or propylene glycol or sorbitol complete or partial ester, preferably, and a tenside having an HLB of at least 10. |
| Inventor(s): | Cavanak; Thomas (Biel-Benken, CH) |
| Assignee: | Novartis AG (Basel, CH) |
| Filing Date: | Apr 19, 2000 |
| Application Number: | 09/552,634 |
| Claims: | 1. A pharmaceutical composition for oral administration comprising cyclosporin A as active ingredient in a carrier medium comprising sorbitol mono-, di-, tri-, and tetra-esters of a fatty acid, wherein the fatty acid is obtained from vegetable oil. 2. The composition according to claim 1 wherein the vegetable oil is selected from the group consisting of corn oil, almond oil, ground-nut oil, olive oil, palm oil, and combinations thereof. 3. The composition according to claim 2 wherein the vegetable oil is olive oil. 4. The composition according to claim 1 which additionally comprises ethanol. 5. The composition according to claim 1 wherein the carrier medium comprises free sorbitol. 6. The composition according to claim 1 wherein the composition is contained in a capsule. 7. A pharmaceutical composition for oral administration comprising cyclosporin A as active ingredient in a carrier medium comprising a reaction product of a natural or hydrogenated castor oil and ethylene oxide; and sorbitol mono-, di-, tri-, and tetra-esters of a fatty acid, wherein the fatty acid is obtained from vegetable oil. |
Serving 500+ biopharmaceutical companies globally:
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