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Serving hundreds of leading biopharmaceutical companies globally:

Daiichi Sankyo
Federal Trade Commission
Harvard Business School

Generated: May 25, 2018

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Details for Patent: 6,096,334

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Title: Adhesive patch for applying medication to the skin and method
Abstract:A non-occlusive medication patch to be applied to the skin includes a porous self-supporting backing layer to give the patch the required integrity and strength by acting as a supporting framework for other components, and a flexible hydrophilic pressure-sensitive adhesive reservoir comprising a natural or synthetic polymer for the sustained release of medication to be absorbed topically through the skin into the body of a patient. The reservoir has two portions: first, an external coating layer with an exposed lower skin-contacting surface that forms a pressure-sensitive bond with the skin, and second, an upper internal portion which infiltrates the porous backing and becomes solidified therein after being applied so that the reservoir and the backing are unified, enabling the backing itself to act as a storage location for the medication-containing reservoir. The medication within the reservoir migrates over time from within the backing through the lower coating layer and passes through the skin to provide sustained release of the medication into the body of a patient.
Inventor(s): Rolf; David (Minneapolis, MN), Sjoblom Urmann; Elisabeth K. (Tomahawk, WI)
Assignee: LecTec Corporation (Minnetonka, MN)
Filing Date:Dec 14, 1998
Application Number:09/211,222
Claims:1. A method of forming a biomedical adhesive patch to be applied to the skin of a patient comprising,

providing a self-supporting flexible sheet to serve as a backing for the patch to give the patch strength by acting as a supporting framework for the patch,

providing an adhesive mass in fluid form, said adhesive mass having a medication dispersed therein,

applying the adhesive mass to the sheet while in a fluid state such that the adhesive mass includes an external exposed pressure-sensitive lower surface for bonding to the skin of the patient, and

solidifying the adhesive mass after application to the sheet so as to comprise a lower portion of said patch while maintaining an upper portion of the backing sheet spaced apart from the adhesive mass.

2. A non-occlusive biomedical adhesive patch to be applied to the skin of a patient for therapeutic purposes comprising,

a backing layer comprising a flexible sheet of water-insoluble material to provide support for the patch,

a flexible pressure-sensitive adhesive layer comprising a natural or synthetic polymer and a biomedically active substance admixed therewith, said layer providing a reservoir for the sustained release of the biomedically active substance for treating the patient,

said pressure-sensitive adhesive is applied to the backing layer and penetrates at least the lower portion of the backing layer,

said pressure-sensitive adhesive is solidified by being cured within the backing layer so as to set up as a solid that is sufficiently dimensionally stable to maintain its own shape and to resist flow during storage for unifying a lower portion of the backing layer,

said backing layer has an upper portion that is free from said pressure-sensitive adhesive, and

a removable liner is bonded to an exposed surface of said pressure-sensitive adhesive layer for being removed from the adhesive layer by pulling it off the patch.

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Serving hundreds of leading biopharmaceutical companies globally:

Johnson and Johnson
Fish and Richardson
US Army

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