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Serving hundreds of leading biopharmaceutical companies globally:

Fish and Richardson
Colorcon
Cantor Fitzgerald
Merck
Baxter
Boehringer Ingelheim
Johnson and Johnson
Daiichi Sankyo
UBS

Generated: June 22, 2018

DrugPatentWatch Database Preview

Details for Patent: 6,083,984

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Title: Triglycerides and ethyl esters of phenylalkanoic acid and phenylalkenoic acid useful in the treatment of various disorders
Abstract:Two new forms of prodrug for phenylacetate, of even congeners of phenylalkanoic acid and phenylalkenoic acids, which are the phenylalkanoic or phenylalkenoic esters of glycerol, or the ethyl esters of phenylalkanoic acid or phenylalkenoic acids. These forms of the drugs provide a convenient dosage form of the drugs. The prodrugs of the invention are useful to treat patients with diseases of nitrogen accumulation, patients with certain .beta.-hemoglobinopathies, anemia, and cancer.
Inventor(s): Brusilow; Saul W. (Baltimore, MD)
Assignee: Brusilow Enterprises LLC (Baltimore, MD)
Filing Date:May 25, 1999
Application Number:09/317,900
Claims:1. A method for the treatment of tumors comprising administering to a patient in need of such treatment an anti-tumor effective amount of a compound of formula I ##STR5## wherein R.sub.1, R.sub.2, and R.sub.3 are independently, H, ##STR6## and n is zero or an even number, m is an even number and at least one of R.sub.1, R.sub.2, and R.sub.3 is not H.

2. A method for the treatment of tumors comprising administering to a patient in need of such treatment an anti-tumor effective amount of a compound of formula II ##STR7## wherein R.sub.4 is ##STR8## wherein n is zero or an even number and m is an even number.

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Serving hundreds of leading biopharmaceutical companies globally:

Johnson and Johnson
McKinsey
Chubb
US Army
Deloitte
Moodys
Dow
Queensland Health
Federal Trade Commission

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