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|Title:||Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension|
|Abstract:||The invention relates to ophthalmological compositions for topical treatment of glaucoma or ocular hypertension comprising an effective intraocular pressure reducing amount of a prostaglandin derivative of PGA, PGB, PGD, PGE or PGF, in which the omega chain contains a ring structure, in an ophthalmologically compatible carrier. The invention further relates to the preparation of said compositions and their use for treatment of glaucoma or ocular hypertension.|
|Inventor(s):||Stjernschantz; Johan Wilhelm (Uppsala, SE), Resul; Bahram (Uppsala, SE)|
|Assignee:||Pharmacia & Upjohn Aktiebolag (Stockholm, SE)|
|Filing Date:||May 10, 1999|
|Claims:||1. A therapeutic composition for topical treatment of ocular hypertension containing a prostaglandin PGF in an amount sufficient to reduce intraocular pressure without causing substantial intraocular irritation, and an ophthamologically compatible vehicle, wherein said prostaglandin is 16-phenoxy, 17, 18, 19-trinorprostaglandin F.sub.2.alpha..|
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