.

Pharmaceutical Business Intelligence

  • Anticipate P&T budget requirements
  • Evaluate market entry opportunities
  • Find generic sources and suppliers
  • Predict branded drug patent expiration

► Plans and Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

DrugPatentWatch Database Preview

Details for Patent: 5,990,096

« Back to Dashboard

Details for Patent: 5,990,096

Title: Formulations containing hyaluronic acid
Abstract:The invention relates to a method of controlling the unloading of a drug from the skin or exposed tissue of a human into the lymphatic system comprising transporting an effective dosage amount of the drug into the skin or exposed tissue by an effective non-toxic amount of a form of hyaluronic acid.
Inventor(s): Asculai; Samuel Simon (Toronto, CA), Hochman; David (Thornhill, CA), Purschke; Don (Toronto, CA), Harper; David William (Oakville, CA), Klein; Ehud Shmuel (Givat Savyon, IL), Falk; Rudolf Edger (Toronto, CA)
Assignee: Hyal Pharmaceutical Corporation (Mississauga, CA)
Filing Date:Jun 06, 1995
Application Number:08/466,713
Claims:1. A dosage amount of pharmaceutical composition suitable for controlling the unloading of a drug from the skin or exposed tissue of a human into the lymphatic system, the dosage amount comprising pharmaceutical excipients suitable for topical application, an effective non-toxic dosage amount of a drug to treat disease in the lymphatic system in human and an effective non-toxic dosage amount of a form of hyaluronic acid selected from the group consisting of hyaluronic acid and salts thereof and combination thereof sufficient to control the unloading of the drug into the lymphatic system wherein the effective amount of the form of hyaluronic acid exceeds 5 mg/cm.sup.2 of the skin or exposed tissue and the molecular weight of the form of hyaluronic acid is greater than 150,000 daltons and less than 750,000 daltons and wherein the form of hyaluronic acid present is between 1% to 3% by weight of the dosage amount.

2. A method of controlling the unloading of a drug from the skin or exposed tissue of a human when applied thereto suffering trauma or pathology, into the lymphatic system comprising transporting an amount of a drug into the skin or exposed tissue by an effective non-toxic dosage amount of a form of hyaluronic acid selected from the group consisting of hyaluronic acid and salts thereof and combination thereof wherein the amount of the form of hyaluronic acid exceeds at least about 5 mg/cm.sup.2 and the molecular weight of the form of hyaluronic acid is greater than 150,000 daltons and less than 750,000 daltons and wherein the form of hyaluronic acid present is between 1% to 3% by weight of the dosage amount.

3. The method of claim 2 wherein the form of hyaluronic acid is sodium hyaluronate being 2.5% by weight of dosage amount and the drug is between 1% to 5% by weight of the dosage amount.

4. The method of claim 3 wherein the drug is a drug which inhibits prostaglandin synthesis.

5. The dosage amount of claim 1 wherein the form of hyaluronic acid is sodium hyaluronate being 2.5% by weight of dosage amount and the drug is between 1% to 5% by weight of the dosage amount and the drug is selected from an NSAID and an anti-cancer drug.

6. The method of claim 4 wherein the drug is selected from an NSAID and an anti-cancer drug.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

How are People Using DrugPatentWatch?

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

`abc