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Generated: August 16, 2017

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Title: Method of treating androgenic alopecia with 5.alpha.-reductase inhibitors
Abstract:The instant invention involves a method of treating and/or reversing androgenic alopecia and promoting hair growth, and methods of treating acne vulgaris, seborrhea, and female hirsutism, by administering to a patient in need of such treatment a 5.alpha.-reductase 2 inhibitor such as finasteride, in a dosage amount under 5 mgs/day.
Inventor(s): Gormley; Glenn J. (Westfield, NJ), Kaufman; Keith D. (Westfield, NJ), Stoner; Elizabeth (Westfield, NJ), Waldstreicher; Joanne (Scotch Plains, NJ)
Assignee: Merck & Co., Inc. (Rahway, NJ)
Filing Date:Jun 22, 1998
Application Number:09/102,454
Claims:1. A method of treating female hirsutism comprising orally administering to a female person in need of such treatment the 5.alpha.-reductase 2 inhibitor 17.beta.-(N-tert-butyl-carbamoyl)-4-aza-5.alpha.-androst-1-ene-3-one in a dosage amount of from about 0.01 to 3.0 mg/day.

2. The method according to claim 1 wherein the dosage amount is from about 0.05 to 1.0 mg/day.

3. The method according to claim 1 wherein the dosage amount is about 0.2 mg/day.

4. The method according to claim 1 wherein the dosage amount is about 1.0 mg.
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Harvard Business School
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