Details for Patent: 5,886,215
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Title: | 2-acetoxymethyl-4-halo-butyl-1-yl acetates |
Abstract: | The present invention provides a process for the synthesis of penciclovir and famciclovir by 9-substituting 2-amino-6-chloropurine (ACP) with an appropriate side chain precursor, followed by conversion of the 6-chloro moiety to a hydroxy moiety (i.e. to form a guanine) or hydrogen (to form a 2-aminopurine), respectively; and 2-acetoxymethyl-4-halo-butyl-1-yl acetates. |
Inventor(s): | Geen; Graham Richard (Stansted Mountfichet, GB2), Jarvest; Richard Lewis (Surbiton, GB2) |
Assignee: | SmithKline Beecham plc (Brentford, GB2) |
Filing Date: | Jun 30, 1997 |
Application Number: | 08/884,731 |
Claims: | 1. A compound known as 2-acetoxymethyl-4-halo-but-1-yl acetate. 2. A compound according to claim 1 wherein halo is bromo. 3. A compound according to claim 1 wherein halo is iodo. |