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Serving hundreds of leading biopharmaceutical companies globally:

US Army
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Fish and Richardson

Generated: March 22, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,886,215

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Title: 2-acetoxymethyl-4-halo-butyl-1-yl acetates
Abstract:The present invention provides a process for the synthesis of penciclovir and famciclovir by 9-substituting 2-amino-6-chloropurine (ACP) with an appropriate side chain precursor, followed by conversion of the 6-chloro moiety to a hydroxy moiety (i.e. to form a guanine) or hydrogen (to form a 2-aminopurine), respectively; and 2-acetoxymethyl-4-halo-butyl-1-yl acetates.
Inventor(s): Geen; Graham Richard (Stansted Mountfichet, GB2), Jarvest; Richard Lewis (Surbiton, GB2)
Assignee: SmithKline Beecham plc (Brentford, GB2)
Filing Date:Jun 30, 1997
Application Number:08/884,731
Claims:1. A compound known as 2-acetoxymethyl-4-halo-but-1-yl acetate.

2. A compound according to claim 1 wherein halo is bromo.

3. A compound according to claim 1 wherein halo is iodo.

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Serving hundreds of leading biopharmaceutical companies globally:

Harvard Business School
Argus Health
US Army

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