Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing
|Title:||Quinoline type mevalonoactones|
|Abstract:||Described herein are mevalonolactone derivatives having a quinoline ring of formula (I) ##STR1## wherein the R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, Y and Z variables are described therein.|
|Inventor(s):||Fujikawa; Yoshihiro (Funabashi, JP), Suzuki; Mikio (Funabashi, JP), Iwasaki; Hiroshi (Funabashi, JP), Sakashita; Mitsuaki (Shiraoka-machi, JP), Kitahara; Masaki (Shiraoka-machi, JP)|
|Assignee:||Nissan Chemical Industries Ltd. (Tokyo, JP)|
|Filing Date:||Dec 19, 1990|
|Claims:||1. A compound of the formula ##STR16## wherein c-Pr is cyclopropyl, and Z is --CH(OH)--CH.sub.2 --CH(OH)--CH.sub.2 --COOH, --CH(OH)--CH.sub.2 -- CH(OH)--CH.sub.2 --COONa, --CH(OH)--CH.sub.2 --CH(OH)--CH.sub.2 --COOR (wherein R is C.sub.1-3 alkyl), or ##STR17## |
2. An anti-hyperlipidemia agent containing the compound of the formula A as defined in claim 1.
3. An anti-hyperlipoproteinemia agent containing the compound of the formula A as defined in claim 1.
4. An anti-atherosclerosis agent containing the compound of the formula A as defined in claim 1.
5. A method for reducing hyperlipidemia, hyperlipoproteinemia or atherosclerosis, which comprises administering an effective amount of the compound of formula A as defined in claim 1.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.