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|Title:||Quinoline type mevalonoactones|
|Abstract:||Described herein are mevalonolactone derivatives having a quinoline ring of formula (I) ##STR1## wherein the R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, Y and Z variables are described therein.|
|Inventor(s):||Fujikawa; Yoshihiro (Funabashi, JP), Suzuki; Mikio (Funabashi, JP), Iwasaki; Hiroshi (Funabashi, JP), Sakashita; Mitsuaki (Shiraoka-machi, JP), Kitahara; Masaki (Shiraoka-machi, JP)|
|Assignee:||Nissan Chemical Industries Ltd. (Tokyo, JP)|
|Filing Date:||Dec 19, 1990|
|Claims:||1. A compound of the formula ##STR16## wherein c-Pr is cyclopropyl, and Z is --CH(OH)--CH.sub.2 --CH(OH)--CH.sub.2 --COOH, --CH(OH)--CH.sub.2 -- CH(OH)--CH.sub.2 --COONa, --CH(OH)--CH.sub.2 --CH(OH)--CH.sub.2 --COOR (wherein R is C.sub.1-3 alkyl), or ##STR17## |
2. An anti-hyperlipidemia agent containing the compound of the formula A as defined in claim 1.
3. An anti-hyperlipoproteinemia agent containing the compound of the formula A as defined in claim 1.
4. An anti-atherosclerosis agent containing the compound of the formula A as defined in claim 1.
5. A method for reducing hyperlipidemia, hyperlipoproteinemia or atherosclerosis, which comprises administering an effective amount of the compound of formula A as defined in claim 1.
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