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US Army
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Generated: April 22, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,869,641

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Title: High affinity nucleic acid ligands of CD4
Abstract:Methods are described for the identification and preparation of high-affinity nucleic acid ligands to CD4. Included in the invention are specific 2'F RNA ligands to CD4 identified by the SELEX method.
Inventor(s): Jayasena; Sumedha (Boulder, CO), Davis; Kenneth A. (Woodside, CA), Gold; Larry (Boulder, CO)
Assignee: NeXstar Pharmaceuticals, Inc. (Boulder, CO)
Filing Date:Feb 14, 1997
Application Number:08/799,949
Claims:1. A purified and isolated non-naturally occurring nucleic acid ligand to CD4, wherein said ligand is an RNA selected from the group consisting of the sequences set forth in Table 2 (SEQ ID NOS:7-24).

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