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Details for Patent: 5,851,839

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Details for Patent: 5,851,839

Title: Platelet aggregation inhibitors
Abstract:Peptides useful in inhibiting platelet aggregation are disclosed. These peptides contain the binding sequence Har-G-D and are disulfide-bridged cyclic compounds.
Inventor(s): Scarborough; Robert M. (Belmont, CA)
Assignee: COR Therapeutics, Inc. (South San Francisco, CA)
Filing Date:Jun 05, 1995
Application Number:08/465,551
Claims:1. A method to detect the presence or absence of the peptide selected from the group consisting of:

which method comprises contacting a sample suspected of containing said peptide with an antibody specifically immunoreactive with said peptide under conditions wherein a complex is formed in the presence of said peptide, and detecting the presence or absence of said complex.

2. The method of claim 1, wherein said peptide is a cyclic peptide comprising a bond between (1) a terminal Mpr and a terminal Cys or (2) a terminal Mpr and a terminal Pen.

3. The method of claim 1, wherein said peptide is selected from the group consisting of:
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