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Details for Patent: 5,801,185

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Details for Patent: 5,801,185

Title: Method of treating Tay-Sachs disease
Abstract:A method is disclosed for the treatment of Tay-Sachs disease comprising subjecting said cells to a glycolipid inhibitory effective amount of an N-alkyl derivative of 1,5-dideoxy-1,5-imino-D-glucitol in which said alkyl contains from 2-8 carbon atoms.
Inventor(s): Platt; Frances M. (Oxford, GB), Neises; Gabrielle R. (Chesterfield, MO), Dwek; Raymond A. (Oxford, GB), Butters; Terry D. (Oxford, GB)
Assignee: Monsanto Company (St. Louis, MO)
Filing Date:Jan 13, 1997
Application Number:08/782,322
Claims:1. A method of treating Tay-Sachs disease in a patient in need thereof comprising administering to said patient a glycolipid inhibitory effective amount of an N-alkyl derivative of 1,5-dideoxy-1,5-imino-D-glucitol in which said alkyl group contains from 2-8 carbon atoms.

2. The method of claim 1 in which the alkyl group contains from 4-6 carbon atoms.

3. The method of claim 2 in which the alkyl group is butyl.

4. The method of claim 2 in which the alkyl group is hexyl.
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