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Generated: September 23, 2017

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Title: Platelet aggregation inhibitors
Abstract:Peptides useful in inhibiting platelet aggregation are disclosed. These peptides contain the binding sequence Har-G-D and are disulfide-bridged cyclic compounds.
Inventor(s): Scarborough; Robert M. (Belmont, CA)
Assignee: COR Therapeutics, Inc. (South San Francisco, CA)
Filing Date:Jun 05, 1995
Application Number:08/462,231
Claims:1. A peptide selected from the group consisting of:

PAI 82 Mpr-A-Har-G-D-W-P-C-NH.sub.2 and (SEQ ID No:3)

PAI 92 Mpr-S-Har-G-D-W-P-C-NH.sub.2. (SEQ ID No:13).

2. The peptide of claim 1, wherein said peptide is a cyclic peptide comprising a bond between a terminal Mpr and a terminal Cys.

3. The peptide of claim 1, wherein said peptide is

PAI 82 Mpr-A-Har-G-D-W-P-C-NH.sub.2. (SEQ ID No:3).

4. The peptide of claim 1, wherein said peptide is

PAI 92 Mpr-S-Har-G-D-W-P-C-NH.sub.2. (SEQ ID No:13).
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