Details for Patent: 5,763,569
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Title: | Calcium receptor-active molecules |
Abstract: | The present invention features calcium receptor polypeptides and fragments thereof. Uses of a calcium receptor polypeptide include providing a polypeptide having the activity of a calcium receptor polypeptide. Calcium receptor polypeptide fragments can be used, for example, to generate antibodies to a calcium receptor polypeptide. |
Inventor(s): | Brown; Edward M. (Milton, MA), Hebert; Steven C. (Wellesley, MA), Garrett, Jr.; James E. (Salt Lake City, UT) |
Assignee: | The Brigham and Women's Hospital, Inc (Boston, MA) NPS Pharmaceuticals, Inc. (Salt Lake City, UT) |
Filing Date: | Jun 07, 1995 |
Application Number: | 08/484,565 |
Claims: | 1. A purified polypeptide comprising at least 12 contiguous amino acids of an amino acid sequence provided in SEQ ID NO: 5. 2. The purified polypeptide of claim 1 comprising at least 18 contiguous amino acids of said amino acid sequence. 3. The purified polypeptide of claim 2 comprising at least 54 contiguous amino acids of said amino acid sequence. 4. A purified polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7 and SEQ ID NO: 8. 5. The polypeptide of claim 4, wherein said amino acid sequence is SEQ ID NO: 5. 6. The polypeptide of claim 4, wherein said amino acid sequence is SEQ ID NO: 6. 7. The polypeptide of claim 4, wherein said amino acid sequence is SEQ ID NO: 7. 8. The polypeptide of claim 4, wherein said amino acid sequence is SEQ ID NO: 8. 9. A purified polypeptide consisting of an amino acid sequence selected from the group consisting of: SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7 and SEQ ID NO: 8. 10. The polypeptide of claim 9, wherein said amino acid sequence is SEQ ID NO: 5. 11. The polypeptide of claim 9, wherein said amino acid sequence is SEQ ID NO: 6. 12. The polypeptide of claim 9, wherein said amino acid sequence is SEQ ID NO: 7. 13. The polypeptide of claim 9, wherein said amino acid sequence is SEQ ID. NO: 8. |