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Details for Patent: 5,760,046

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Details for Patent: 5,760,046

Title: Method of treating androgenic alopecia with 5-.alpha.reductase inhibitors
Abstract:The instant invention involves a method of treating and/or reversing androgenic alopecia and promoting hair growth, and methods of treating acne vulgaris, seborrhea, and female hirsutism, by administering to a patient in need of such treatment a 5.alpha.-reductase 2 inhibitor, such as finasteride, in a dosage amount under 5 mgs/day.
Inventor(s): Gormley; Glenn J. (Westfield, NJ), Kaufman; Keith D. (Westfield, NJ), Stoner; Elizabeth (Westfield, NJ), Waldstreicher; Joanne (Scotch Plains, NJ)
Assignee: Merck & Co., Inc. (Rahway, NJ)
Filing Date:Feb 14, 1996
Application Number:08/601,497
Claims:1. A method of treating female pattern baldness comprising orally ale person in need of such treatment the 5.alpha.-reductase 2 inhibitor 17.beta.(N-tert.-butylcarbamoyl)-4-aza-5.alpha.-androst 1-ene-3-one in a dosage amount from 0.01 to 3 mgs/day.

2. The method of claim 1 wherein the dosage amount is from about 0.05 to 1.0 mg/day.

3. The method of claim 1 wherein the dosage amount is about 0.05 mg/day.

4. The method of claim 1 wherein the dosage amount is about 0.2 mgs/day.

5. A method of arresting and reversing female pattern baldness comprising orally administering to a female person in need of such treatment the 5.alpha.-reductase 2 inhibitor 17.beta.-(N-tert.-butylcarbamoyl)-4-aza-5.alpha.-androst-1-ene-3-one in an amount from 0.01 to 3 mgs/day.

6. The method of claim 5 wherein the dosage amount is about 0.2 mg/day.

7. The method of claim 5 wherein the dosage amount is about 0.05 mg/day.

8. The method of claim 1 wherein the dosage amount is about 1.0 mg/day.

9. The method of claim 5 wherein the dosage amount is about 1.0 mg/day.
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