Generated: April 26, 2017
|Abstract:||1.alpha.-Hydroxy-24-epi-vitamin D.sub.4 and novel intermediates formed in a novel method of preparing this compound. The method includes campesterol as a starting material which is converted to 24-epi-vitamin D.sub.4 which is in turn hydroxylated to 1.alpha.-hydroxy-24-epi-vitamin D.sub.4 via tosylated and cyclic derivatives of 24-epi-vitamin D.sub.4. 1.alpha.-Hydroxy-24-epi-vitamin D.sub.4 has been found to be bioactive.|
|Inventor(s):||Knutson; Joyce C. (Madison, WI), Moriarty; Robert M. (Oak Park, IL), Penmasta; Raju (Oak Park, IL), Bishop; Charles W. (Verona, WI)|
|Assignee:||Bone Care International, Inc. (Madison, WI)|
|Filing Date:||Sep 07, 1995|
|Claims:||1. The compound of the formula (I): ##STR3## wherein R.sub.1 is either hydrogen or tosyl and R.sub.2 is either hydrogen or hydroxy, or a salt, hydrate, or solvate thereof. |
2. The compound of claim 1, wherein the compound is 1.alpha.-hydroxy-24-epi-vitamin D.sub.4.
3. 5,6-trans-1.alpha.-hydroxy-24-epi-vitamin D.sub.4.
4. 24-epi-vitamin D.sub.4 tosylate.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.