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Serving hundreds of leading biopharmaceutical companies globally:

Fish and Richardson
US Department of Justice
Harvard Business School

Generated: June 22, 2018

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Details for Patent: 5,728,756

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Title: Antiplaque antibacterial oral composition
Abstract:An oral composition dentifrice comprising an orally acceptable vehicle, about 5-30% by weight of a siliceous polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxydiphenyl ether (triclosan), and an antibacterial-enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, wherein said antiplaque agent is substantially completely dissolved in saliva present during tooth and gum cleaning in a solubilizing agent therefor. The solubilizing agent may be a humectant polyol such as propylene glycol, dipropylene glycol and hexylene glycol; a cellosolve such as methy cellosolve and ethyl cellosolve: a vegetable oil or wax containing at least about 12 carbon atoms in a straight chain such as olive oil, castor oil and petrolatum; or an ester such as ethyl acetate, amyl acetate, glyceryl tristearate and benzyl benzoate.
Inventor(s): Gaffar; Abdul (Princeton, NJ), Nabi; Nuran (Brunswick, NJ), Afflitto; John (Brookside, NJ), Stringer; Orum (Yardley, PA)
Assignee: Colgate Palmolive Company (New York, NY)
Filing Date:Jun 24, 1996
Application Number:08/668,754
Claims:1. Beta styrene phosphonic acid/vinyl phosphonic acid copolymer, said copolymer being water-soluble and having a molecular weight of about 2,000 to about 30,000.

2. A method of preparing a polymer as defined in claim 1 comprising polymerizing the precursor mixture of monomers at elevated temperatures in the presence of a radical initiator, mixing the crude polymeric product with water, adjusting the resulting solution of pH of about 8-11, dialyzing the solution against water and isolating the purified copolymer therefrom.

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Serving hundreds of leading biopharmaceutical companies globally:

Fish and Richardson
Chinese Patent Office
US Department of Justice

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