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Serving hundreds of leading biopharmaceutical companies globally:

Daiichi Sankyo

Generated: May 20, 2018

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Details for Patent: 5,705,658

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Title: Azido containing tetrahydro furan compounds
Abstract:.delta.-Amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acid amides of formula I ##STR1## and the salts thereof, have renin-inhibiting properties and can be used as antihypertensive medicinal active ingredients.
Inventor(s): Goschke; Richard (Bottmingen, CH), Maibaum; Jurgen Klaus (Weil-Haltingen, DE), Schilling; Walter (Himmelried, CH), Stutz; Stefan (Basel, CH), Rigollier; Pascal (Sierentz, FR), Yamaguchi; Yasuchika (Basel, CH), Cohen; Nissim Claude (Village-Neuf, FR), Herold; Peter (Arlesheim, CH)
Assignee: Novartis Corporation (Summit, NJ)
Filing Date:Feb 14, 1997
Application Number:08/800,671
Claims:1. A compound of formula XVI ##STR39## R is H, C.sub.1 -C.sub.4 alkyl or acetyl, R.sub.1 and R.sub.4 are hydrogen,

R.sub.2 is C.sub.1 -C.sub.4 alkoxy-C.sub.1 -C.sub.4 alkoxy,

R.sub.3 is C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy or benzyloxy-C.sub.1 -C.sub.4 alkoxy, and

R.sub.5 is isopropyl,

or a salt thereof.

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US Army
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