Details for Patent: 5,705,658
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Title: | Azido containing tetrahydro furan compounds |
Abstract: | .delta.-Amino-.gamma.-hydroxy-.omega.-aryl-alkanoic acid amides of formula I ##STR1## and the salts thereof, have renin-inhibiting properties and can be used as antihypertensive medicinal active ingredients. |
Inventor(s): | Goschke; Richard (Bottmingen, CH), Maibaum; Jurgen Klaus (Weil-Haltingen, DE), Schilling; Walter (Himmelried, CH), Stutz; Stefan (Basel, CH), Rigollier; Pascal (Sierentz, FR), Yamaguchi; Yasuchika (Basel, CH), Cohen; Nissim Claude (Village-Neuf, FR), Herold; Peter (Arlesheim, CH) |
Assignee: | Novartis Corporation (Summit, NJ) |
Filing Date: | Feb 14, 1997 |
Application Number: | 08/800,671 |
Claims: | 1. A compound of formula XVI ##STR39## R is H, C.sub.1 -C.sub.4 alkyl or acetyl, R.sub.1 and R.sub.4 are hydrogen, R.sub.2 is C.sub.1 -C.sub.4 alkoxy-C.sub.1 -C.sub.4 alkoxy, R.sub.3 is C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy or benzyloxy-C.sub.1 -C.sub.4 alkoxy, and R.sub.5 is isopropyl, or a salt thereof. |