|Title:|| Controlled release formulations for the treatment of xerostomia|
|Abstract:||A polymeric delivery system which is formed by a polycarbophil type composition with an active agent, optionally in the presence of water and/or other cosolvent. The resulting product is especially useful as a carrier or coating of active compositions, such as pharmaceuticals and the like. The composition is also useful for the controlled or sustained release of active agents that are drugs, cosmetic agents, household agents, agricultural agents, industrial chemical agents and nutritional agents. A composition and method for the treatment of xerostomia is also disclosed, comprising polycarbophil in the form of an article having a shape suitable for insertion into the mouth.|
|Inventor(s):|| Acharya; Ramesh N. (Lake Forest, IL) |
|Assignee:|| Theratech, Inc. (Salt Lake City, UT) |
|Filing Date:||Apr 01, 1991|
|Claims:||1. A method for treating xerostomia comprising contacting an oral mucosa of a patient with a shaped polymeric delivery system/device comprising calcium polycarbophil containing about 1 to about 10 ml of water and maintaining said polymeric delivery system/device in contact with the oral mucosa thereby to hydrate the oral mucosa with a sufficient amount of water to treat xerostomia. |
2. The method of claim 1, wherein the shaped system/device further comprises an active medicament.
3. The method of claim 1, wherein the shaped system/device further comprises a lubricant.
4. The method of claim 1, wherein the shaped system/device further comprises a flavorant.