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|Title:||Treatment of viral infections|
|Abstract:||Treatment of animals or humans carrying or infected with HTLV-I, HTLV-I (including HTLV-I-associated leukemias or lymphomas), non-A, non-B hepatitis virus, hepatitis B virus, EBV, equine infectious anaemia or other lentiviruses or having antibodies to said viruses is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof. Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.|
|Inventor(s):||Rideout; Janet Litster (Raleigh, NC), Barry; David Walter (Chapel Hill, NC), Lehrman; Sandra Nusinoff (Durham, NC), St. Clair; Martha Heider (Durham, NC), Furman; Phillip Allen (Durham, NC)|
|Assignee:||Glaxo Wellcome Inc. (Research Triangle Park, NC)|
|Filing Date:||Feb 26, 1993|
|Claims:||1. A method of treating an HTLV-I infection in a host in need thereof comprising administering to said host an effective treatment amount of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable salt thereof. |
2. The method of claim 1, in which the compound or salt is administered orally or parenterally.
3. The method of claim 1, in which the compound or salt is administered orally or parenterally.
4. A method of treating an HTLV-II infection in a host in need thereof comprising administering to said host an effective HTLV-II treatment amount of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable salt thereof.
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