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Details for Patent: 5,641,744

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Details for Patent: 5,641,744

Title: Treatment of diabetes mellitus
Abstract:The present invention relates to methods of preparing a product or a composition containing amylin or amylin with insulin for treating diabetes mellitus.
Inventor(s): Cooper; Garth J. S. (Woodstock, GB2)
Assignee: Amylin Pharmaceuticals, Inc. (San Diego, CA)
Filing Date:Nov 17, 1994
Application Number:08/341,342
Claims:1. A method of preparing a product for treatment of a patient suffering from diabetes mellitus which comprises bringing a predetermined amount of an amylin agonist into the form of a composition suitable for parenteral administration to said diabetic patient.

2. The method of claim 1 wherein said amylin agonist is amylin.

3. The method of claim 1 wherein said amylin agonist is a conservative variant of amylin.

4. The method of claim 2 wherein said amylin is human amylin.

5. The method of claim 1 wherein said amylin agonist is CGRP.

6. The method of claim 1 wherein said amylin agonist is a conservative variant of CGRP.

7. The method of claim 5 wherein said CGRP is human CGRP.

8. The method of claim 1 wherein said parenteral administration is subcutaneous.

9. A method of preparing a composition for treatment of a patient suffering from diabetes mellitus which comprises bringing a predetermined amount of an insulin and a predetermined amount of an amylin agonist into the form of a composition suitable for parenteral administration to said diabetic patient.

10. The method of claim 9 wherein said amylin agonist is amylin.

11. The method of claim 9 wherein said amylin agonist is a conservative variant of amylin.

12. The method of claim 10 wherein said amylin is human amylin.

13. The method of claim 9 wherein said amylin agonist is CGRP.

14. The method of claim 9 wherein said amylin agonist is a conservative variant of CGRP.

15. The method of claim 13 wherein said CGRP is human CGRP.

16. The method of claim 9 wherein said insulin and said amylin agonist are in a ratio of from 100:1 to 0.1:1.

17. The method of claim 9 wherein said parenteral administration is subcutaneous.
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