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Generated: October 23, 2018

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Details for Patent: 5,597,898

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Title: NF-.kappa.B activation regulatory protein, I.kappa.B-.beta.
Abstract:The present invention provides a novel polypeptide, I.kappa.B-.beta., which binds to and affects NF-.kappa.B gene activation. Also provided is the nucleotide sequence encoding I.kappa.B-.beta. and methods of identifying compositions which affect I.kappa.B-.beta..backslash.NF-.kappa.B complexes. Methods of treatment of disorders associated with NF-.kappa.B induced gene activation are also described herein.
Inventor(s): Ghosh; Sankar (Madison, CT)
Assignee: Yale University (New Haven, CT)
Filing Date:Feb 15, 1995
Application Number:08/388,756
Claims:1. An isolated I.kappa.B-.beta. polypeptide having the amino acid sequence of SEQ ID NO: 2.

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