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|Title:||Method for treating neurological disorders|
|Abstract:||A method for ameliorating a neurological disorder in a human by administration to the cerebrospinal fluid (CSF) of a therapeutic agent in a dispersion system which allows the therapeutic agent to persist in the cerebro-ventricular space.|
|Inventor(s):||Kim; Sinil (Solana Beach, CA), Howell; Stephen B. (Del Mar, CA)|
|Assignee:||DepoTech Corporation (San Diego, CA)|
|Filing Date:||Jun 07, 1995|
|Claims:||1. A method for ameliorating a viral disease which comprises intralumbar administration to the cerebrospinal fluid (CSF) of a human with the disease of a therapeutically effective amount of an antiviral drug in a synthetic membrane vesicle such that the antiviral agent persists in the cerebro-ventricular space for a time sufficient to ameliorate the disease. |
2. The method of claim 1 wherein the synthetic membrane vesicle is a liposome.
3. The method of claim 2 wherein the synthetic membrane vesicle contains multiple concentric chambers.
4. The method of claim 3 wherein the synthetic membrane vesicle contains multiple non-concentric chambers.
5. The method of claim 1 wherein the antiviral agent is cytarabine.