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|Title:||Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analgetics|
|Abstract:||Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents, the compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one of the compounds. Depot derivatives of the compounds are useful for providing long acting effects of the compounds. The compounds are also useful as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal.|
|Inventor(s):||Strupczewski; Joseph T. (Flemington, NJ), Helsley; Grover C. (Stockton, NJ), Glamkowski; Edward J. (Warren, NJ), Chiang; Yulin (Covent Station, NJ), Bordeau; Kenneth J. (Kintnersville, PA), Nemoto; Peter A. (Raritan, NJ), Tegeler; John J. (Bridgewater, NJ)|
|Assignee:||Hoechst-Roussel Pharmaceuticals, Inc. (Sommerville, NJ)|
|Filing Date:||Dec 22, 1995|
|Claims:||1. 2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]acetonitrile and its pharmaceutically acceptable acid addition salts. |
2. 3-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propionitrile and its pharmaceutically acceptable acid addition salts.
3. [4-(6-Fluoro-1H-indazol-3-yl)-1-piperazinyl]acetonitrile and its pharmaceutically acceptable acid addition salts.
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