.

Deeper Knowledge, Faster

  • Analyze global market entry opportunities
  • Uncover prior art in expired and abandoned patents
  • Obtain formulation and manufacturing information

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving leading biopharmaceutical companies globally:

Moodys
Argus Health
Express Scripts
Harvard Business School
Chinese Patent Office
Dow
Boehringer Ingelheim
Fuji
US Department of Justice
Healthtrust

Generated: November 24, 2017

DrugPatentWatch Database Preview

Details for Patent: ► Subscribe

« Back to Dashboard

Details for Patent: ► Subscribe

Title: Method and compositions for the synthesis of BCH-189 and related compounds
Abstract:The present invention relates to a method of preparing BCH-189 and various analogs of BCH-189 from inexpensive precursors with the option of introducing functionality as needed. This synthetic route allows the stereoselective preparation of the biologically active isomer of these compounds, .beta.-BCH-189 and related compounds. Furthermore, the steochemistry at the nucleoside 4' position can be controlled to produce enantiomerically-enriched .beta.-BCH-189 and its analogs.
Inventor(s): Liotta; Dennis C. (Stone Mountain, GA), Choi; Woo-Baeg (Atlanta, GA)
Assignee: Emory University (Atlanta, GA)
Filing Date:Feb 10, 1993
Application Number:08/015,992
Claims:1. The (-)-enantiomer of the .beta.-isomer of 2',3'-dideoxy-3'-thia-cytidine (BCH-189).

2. The (-)-enantiomer of the .beta.-isomer of 2',3'-dideoxy-3'-thia-cytidine (BCH-189), in substantially pure form.

3. The (-)-enantiomer of the .beta.-isomer of 2',3'-dideoxy-3'-thia-cytidine substantially free of the (+)-enantiomer of the .beta.-isomer of 2',3'-dideoxy-3'-thia-cytidine.

4. A composition consisting essentially of the (-)-enantiomer of the .beta.-isomer of 2',3'-dideoxy-3'-thia-cytidine.

5. .beta.-BCH-189 substantially in the form of one optical isomer.

6. A composition consisting essentially of one optical isomer of .beta.-BCH-189.

7. Enantiomerically enriched .beta.-BCH-189.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

Serving leading biopharmaceutical companies globally:

Healthtrust
Daiichi Sankyo
Fish and Richardson
Cantor Fitzgerald
McKinsey
Boehringer Ingelheim
Accenture
Baxter
Queensland Health
Teva

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

Copyright 2002-2017 thinkBiotech LLC
ISSN: 2162-2639

Secure SSL Encrypted
Privacy and Cookies
Terms & Conditions

Follow DrugPatentWatch:



Google
Twitter
Google Plus
botpot