Anticipate generic drug launch
Find generic entry opportunities
Drug patents …
… from Kazakhstan to Kalamazoo
Deep knowledge on
small-molecule drugs and
the 110,000 global patents
Proactively manage your pharmacy inventory
Manage your formulary budget
Flat-rate pricing for predictable budgeting
Short-term plans for project- or client-based billing
Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing
|Title:||Surface modified anticancer nanoparticles|
|Abstract:||Dispersible particles consisting essentially of a crystalline anticancer agent having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 1000 nm. Anticancer compositions comprising the particles exhibit reduced toxicity and/or enhanced efficacy, and can be administered by IV bolus injection.|
|Inventor(s):||Liversidge; Gary G. (West Chester, PA), Liversidge; Elaine (West Chester, PA), Sarpotdar; Pramod P. (Malvern, PA)|
|Assignee:||Eastman Kodak Company (Rochester, NY)|
|Filing Date:||Dec 28, 1994|
|Claims:||1. Particles consisting essentially of a crystalline piposulfan having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an average effective particle size of less than 1000 nm. |
2. The particles of claim 1 wherein said surface modifier comprises in combination a polyoxyethylene sorbitan fatty acid ester and a sorbitan ester of a fatty acid; wherein the fatty acid contains 12 to 18 carbon atoms.
3. The particles of claim 1 wherein said surface modifier is polyvinyl alcohol.
4. The particles of claim 1 wherein said surface modifier is gum acacia.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.