Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving hundreds of leading biopharmaceutical companies globally:

Farmers Insurance
Chinese Patent Office
US Department of Justice
Queensland Health

Generated: May 25, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,489,614

« Back to Dashboard

Title: Catechol derivatives, their physiologically acceptable salts, esters and use
Abstract:Known and new catechol derivates may be used as medicinal antioxidants in the prevention or treatment of tissue damage induced by lipid peroxidation. The conditions and diseases to be treated are for example heart disease, rheumatoid arthritis, cancer, inflammatory disease, a rejection reaction in organ transplants, ischemia, cancer and aging.
Inventor(s): Korkolainen; Tapio J. (Helsinki, FI), Nissinen; Erkki A. O. (Espoo, FI), Backstrom; Reijo J. (Helsinki, FI), Pippuri; Aino K. (Espoo, FI)
Assignee: Orion-yhtyma Oy (Espoo, FI)
Filing Date:Jun 05, 1995
Application Number:08/461,752
Claims:1. A method for the prevention or treatment of tissue damage induced by lipid peroxidation associated with ischemia by administering to a patient in need of such prevention or treatment an effective amount to prevent or treat tissue damage induced by lipid peroxidation of the compound of formula I ##STR11## wherein R.sub.3 is cyano or lower acyl and R.sub.4 is lower acyl or carbamoyl which is unsubstituted or substituted by lower alkyl or lower hydroxyalkyl or a physiologically acceptable salt or ester thereof.

2. The method according to claim 1, in which the compound is 3-(3,4-dihydroxy-5-nitrophenyl)methylene-2,4-pentanedione.

For more information try a trial or see the plans and pricing

Serving hundreds of leading biopharmaceutical companies globally:

Farmers Insurance
Fish and Richardson
Express Scripts
Federal Trade Commission

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.