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Details for Patent: 5,362,634

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Details for Patent: 5,362,634

Title: Process for producing A83543 compounds
Abstract:Fermentation product A83543, comprising major components A83543A and A83543D and minor components A83543B, A83543C, A83543E, A983543F, A83543G, A83543H and A83543J, is produced by a newly described species, Saccharopolyspora spinosa. The A83543 components and their acid-addition salts (A83543 compounds) are useful as insecticides, particularly against Lepidoptera and Diptera species. Insecticidal, miticidal or ecto-parasiticidal combinations, compositions and methods are provided.
Inventor(s): Boeck; LaVerne D. (Indianapolis, IN), Chio; Hang (Greenfield, IN), Eaton; Tom E. (Greenwood, IN), Godfrey, Jr.; Otis W. (Greenwood, IN), Michel; Karl H. (Indianapolis, IN), Nakatsukasa; Walter M. (Indianapolis, IN), Yao; Raymond C. (Carmel, IN)
Assignee: DowElanco (Indianapolis, IN)
Filing Date:Oct 10, 1991
Application Number:07/773,754
Claims:1. A process for producing fermentation product A83543, comprising A83543A, A83543B, A83543C, A83543D, A83543E, A83543F, A83543G, A83543H, and A83543J which comprises cultivating a Saccharopolyspora spinosa strain selected from NRRL 18395, NRRL 18537, NRRL 18538 or NRRL 18539, or an A83543-producing strain derived therefrom, in a culture medium containing assimilable sources of carbon, nitrogen, and inorganic salts under submerged aerobic fermentation conditions until a recoverable amount of A83543 is produced.

2. A process of claim 1 which includes the additional step of separating A83543 from the culture medium.

3. The process of claim 2 which includes the additional step of separating A83543A from A83543.

4. The process of claim 2 which includes the additional step of separating A83543D from A83543.

5. A process of claim 2 which includes the additional step of separating A83543B from A83543.

6. A process of claim 2 which includes the additional step of separating A83543C from A83543.

7. A process of claim 2 which includes the additional step of separating A83543E from A83543.

8. A process of claim 2 which includes the additional step of separating A83543F from A83543.

9. A process of claim 2 wheich includes the additional step of separating A83543G from A83543.

10. A process of claim 1 wherein the culture is NRRL 18395 or an A83543-producing strain derived therefrom.

11. A process of claim 1 wherein the culture is NRRL 18537 or an A83543-producing strain derived therefrom.

12. A process of claim 1 wherein the culture is NRRL 18538 or an A83543-producing strain derived therefrom.

13. A process of claim 1 wherein the culture is NRRL 18539 or an A83543-producing strain derived therefrom.

14. A biologically purified culture of Saccharopolyspora spinosa selected from NRRL 18395, NRRL 18537, NRRL 18538, or NRRL 18539, or an A83543-producing strain derived therefrom.

15. The culture of claim 14 which is S. spinosa NRRL 18395 or an A83543-producing strain derived therefrom.

16. The culture of claim 14 which is S. spinosa NRRL 18537 or an A83543-producing strain derived therefrom.

17. The culture of claim 14 which is S. spinosa NRRL 18538 or an A83543-producing strain derived therefrom.

18. The culture of claim 14 which is S. spinosa NRRL 18539 or an A83543-producing strain derived therefrom.
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