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Generated: November 24, 2017

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Title: Medicaments
Abstract:A method for treating or preventing a Pneumocystis carinii infection in a mammal by administering a certain naphthoquinone compound or physiologically acceptable salts thereof.
Inventor(s): Latter; Victoria S. (Beckenham, GB2), Gutteridge; Winston E. (Beckenham, GB2), Hudson; Alan T. (Beckenham, GB2)
Assignee: Burroughs Wellcome Co. (Research Triangle Park, NC)
Filing Date:Nov 22, 1991
Application Number:07/796,324
Claims:1. A method of treating in a mammal Pneumocystis carinii infections which comprises administering to said mammal suffering with P. carinii an effective treatment amount of a naphthoquinone of the general formula: ##STR8## wherein R.sup.10 is an alkyl group of from 1 to 10 carbon atoms and m is 0 to 1; and physiologically acceptable salts thereof.

2. A method according to claim 1 wherein the naphthoquinone is 2-(4-t-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone.

3. A method according to any one of claims 1 or 2 wherein the compound of formula is administered in an amount of from 10 to 50 mg per kilogram of mammal body weight per day.

4. A method according to claim 2 or 3 wherein the mammal is a human.
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US Army
Daiichi Sankyo
Queensland Health
Teva
Deloitte
Moodys
Fish and Richardson
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Citi
Baxter

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