.

Pharmaceutical Business Intelligence

  • Anticipate P&T budget requirements
  • Evaluate market entry opportunities
  • Find generic sources and suppliers
  • Predict branded drug patent expiration

► Plans and Pricing

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

DrugPatentWatch Database Preview

Details for Patent: 5,270,315

« Back to Dashboard

Details for Patent: 5,270,315

Title: 4-(purinyl bases)-substituted-1,3-dioxlanes
Abstract:There is provided novel 2-substituted-4-substituted-1,3-dioxolanes which are particularly useful as antiviral agents.
Inventor(s): Belleau; Bernard (Westmont, CA), Dixit; Dilip (Montreal, CA), Nguyen-Ba; Nghe (Brossard, CA)
Assignee: BioChem Pharma Inc. (Laval, CA)
Filing Date:Mar 07, 1991
Application Number:07/666,045
Claims:1. A 1,3-dioxolane derivative of the general formula (L), the geometric and optical isomers thereof and mixtures of those isomers: ##STR11## wherein: R.sub.1 is selected from the group consisting of hydrogen, an aliphatic acyl group having 2 to 16 carbon atoms, benzoyl and a benzoyl substituted in any position by a halogen, a lower alkyl, lower alkoxy, a nitro or a trifluoromethyl group;

R.sub.2 is a heterocyclic radical selected from: ##STR12## wherein R.sub.3 is selected from the group consisting of hydrogen and lower alkyl radicals having from 1 to 3 carbon atoms;

R.sub.4 is selected from the group consisting of hydrogen and lower alkyl or alkenyl radicals having from 1 to 3 carbon atoms; and

R.sub.5 is selected from the group consisting of lower alkyl or alkenyl radicals having from 1 to 3 carbon atoms, fluoro and iodo.

2. The compound of claim 1 which is the 2-benzoyloxymethyl-4-(adenin-9'-yl)-1,3-dioxolane.

3. The compound of claim 1 which is the 2-hydroxymethyl-4-(adenin-9'-yl)-1,3-dioxolane.

4. The compound of claim 1 which is the 2-benzoyloxymethyl-4-(2'-amino-6'-chloro-(purin-9'-yl)-1,3-dioxolane.

5. The compound of claim 1 which is the 2-hydroxymethyl-4-(2'-amino-6'-chloro-(purin-9'-yl)-1,3-dioxolane.

6. The compound of claim 1 which is the 2-hydroxymethyl-4-(2'-amino-purin-9'-yl)-1,3-dioxolane.

7. The compound of claim 1 which is the 2-hydroxymethyl-4-(2',6'-diamino-purin-9'-yl)-1,3-dioxolane.

8. The compound of claim 1 which is the 2-hydroxymethyl-4-(guanin-9'-yl)-1,3-dioxolane.
« Back to Dashboard

For more information try a trial or see the database preview and plans and pricing

How are People Using DrugPatentWatch?

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

`abc