.

Make Better Decisions

  • Analyze global market entry opportunities
  • Uncover prior art in expired and abandoned patents
  • Drug patents in 130+ countries

Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving leading biopharmaceutical companies globally:

Fish and Richardson
Cerilliant
Chinese Patent Office
Cipla
McKinsey
Federal Trade Commission
Daiichi Sankyo
Queensland Health
Medtronic
QuintilesIMS

Generated: January 20, 2018

DrugPatentWatch Database Preview

Details for Patent: ➤ Subscribe

« Back to Dashboard

Details for Patent: ➤ Subscribe

Title: Triazole antifungal agents
Abstract:The invention provides antifungal agents of the formula: ##STR1## and their pharmaceutically acceptable salts, wherein R is phenyl optionally substituted by 1 to 3 substituents each independently selected from halo and CF.sub.3 ; R.sup.1 is C.sub.1 -C.sub.4 alkyl; R.sup.2 is H or C.sub.1 -C.sub.4 alkyl; and "Het", which is attached to the adjacent carbon atom by a ring carbon atom, is selected from pyridinyl, pyridazinyl, pyrimidinyl, pyrazinyl and triazinyl, "Het" being optionally substituted by C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, halo, CF.sub.3, CN, NO.sub.2, NH.sub.2, --NH(C.sub.1 -C.sub.4 alkanoyl) or --NHCO.sub.2 (C.sub.1 -C.sub.4 alkyl).
Inventor(s): Dickinson; Roger P. (Dover, GB2), Richardson; Kenneth (Birchington, GB2)
Assignee: Pfizer Inc. (New York, NY)
Filing Date:Mar 04, 1992
Application Number:07/845,986
Claims:1. A compound of the formula ##STR41## or a pharmaceutically acceptable acid addition salt thereof, wherein R is chlorophenyl, fluorophenyl, dichlorophenyl or difluorophenyl; R.sup.1 is alkyl having one to four carbon atoms; R.sup.2 is hydrogen or alkyl having one to four carbon atoms; and Het is triazinyl, optionally substituted with a fluoro, chloro, bromo, alkyl having from one to four carbon atoms, alkoxy having from one to four carbon atoms, trifluoromethyl, nitro, alkanoylamino having one to four carbon atoms, alkoxycarbonylamino having two to five carbon atoms, amino or cyano group.

2. A compound of claim 1, wherein R.sup.1 is methyl and R.sup.2 is hydrogen.

3. A compound of claim 1, wherein the stereoconfiguration is ##STR42##

4. A compound of claim 3, wherein R.sup.1 is methyl and R.sup.2 is hydrogen.
« Back to Dashboard

For more information try a trial or see the plans and pricing

Serving leading biopharmaceutical companies globally:

Baxter
US Department of Justice
McKesson
QuintilesIMS
Harvard Business School
Colorcon
Daiichi Sankyo
Dow
Covington
Boehringer Ingelheim

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

Copyright 2002-2018 thinkBiotech LLC
ISSN: 2162-2639

Secure SSL Encrypted
Privacy and Cookies
Terms & Conditions

Follow DrugPatentWatch:

botpot