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Generated: March 17, 2018

DrugPatentWatch Database Preview

Details for Patent: 5,142,046

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Title: Optically active pyridobenzoxazine derivatives and intermediates thereof
Abstract:An optically action pyridobenzoxazine derivative, a process for preparing the same and a novel intermediate useful for preparing the optically active pyridobenzoxazine derivative are disclosed. The optically active pyridobenzoxazine derivative possesses increased antimicrobial activity and reduced toxicity. The intermediate is useful for preparing such optically active pyridobenzoxazine derivatives such as Ofloxacin and anolog compounds.
Inventor(s): Hayakawa; Isao (Tokyo, JP), Atarashi; Shohgo (Tokyo, JP), Imamura; Masazumi (Tokyo, JP), Yokohama; Shuichi (Tokyo, JP), Higashihashi; Nobuyuki (Tokyo, JP), Sakano; Katsuichi (Tokyo, JP), Ohshima; Masayuki (Tokyo, JP)
Assignee: Daiichi Pharmaceutical Co., Ltd. (Tokyo, JP)
Filing Date:Aug 28, 1991
Application Number:07/754,198
Claims:1. An S(-)-optically pure 4-substituted benzoxazine derivative represented by the formula (X) ##STR9## wherein X.sub.1 and X.sub.2, which may be the same or different, each represents a halogen atom, R.sub.1 represents an alkyl group having 1 to 4 carbon atoms, and Q represents a hydrogen atom.

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Serving hundreds of leading biopharmaceutical companies globally:

Harvard Business School
Chinese Patent Office
US Department of Justice
Farmers Insurance

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