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Details for Patent: 5,124,314

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Details for Patent: 5,124,314

Title: Pharmaceutical compositions containing amylin
Abstract:The present invention relates to pharmaceutical compositions for use in treating diabetes Mellitus or hypoglycemia containing Amylin as the effective additive.
Inventor(s): Cooper; Garth J. S. (Solana Beach, CA)
Assignee: Amylin Pharmaceuticals, Inc. (San Diego, CA)
Filing Date:Jun 10, 1991
Application Number:07/715,031
Claims:1. A pharmaceutical composition for use in the treatment of diabetes mellitus or hypoglycemia which comprises a therapeutically effective amount of amylin in association with a pharmaceutically acceptable carrier.

2. A pharmaceutical composition for use in the treatment of diabetes mellitus or hypoglycemia which comprises therapeutically effective amount of amylin and a therapeutically effective amount of an insulin in association with a pharmaceutically acceptable carrier.

3. The pharmaceutical composition of claim 1 wherein said composition is lyophilized.

4. The pharmaceutical composition of claim 2 wherein said composition is lyophilized.

5. The pharmaceutical composition of claim 1 wherein said composition is disposed in a vehicle suitable for delayed-release administration.

6. The pharmaceutical composition of claim 2 wherein said composition is disposed in a vehicle suitable for delayed-release administration.

7. The pharmaceutical composition of claim 1 which comprises a suspension of said amylin, said suspension being formulated with a zinc salt in a pharmaceutically acceptable buffer, and said suspension being suitable for parenteral administration.

8. The pharmaceutical composition of claim 2 which comprises a suspension of said amylin and said insulin, said suspension being formulated with a zinc salt in a pharmaceutically acceptable buffer, and said suspension being suitable for parenteral administration.

9. The pharmaceutical composition of any of claims 1-7 or 8 wherein said amylin is human amylin.
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