Generated: April 24, 2017
|Abstract:||Novel .beta.-lactam compounds belonging to carbapenem or penem derivatives useful as antimicrobial agents or intermediates therefor and a process for producing these compounds are disclosed.|
|Inventor(s):||Sunagawa; Makoto (Osaka, JP), Matsumura; Haruki (Osaka, JP), Inoue; Takaaki (Hyogo, JP), Fukasawa; Masatomo (Hyogo, JP), Kato; Masuhiro (Osaka, JP)|
|Assignee:||Sumitomo Pharmaceuticals Co., Ltd. (Osaka, JP)|
|Filing Date:||May 21, 1990|
|Claims:||1. A compound of the formula: ##STR386## wherein R1 represents 1-hydroxyethyl or a protected 1-hydroxyethyl; R2and R3 each independently represent a hydrogen atom or a protecting group; X represents an alkyl (C1-C3) substituted or unsubstituted methylene group; Y represents (1) an unsubstituted or alkyl (C1-C3) substituted guanidyl group, (2) an unsubstituted or substituted hydrazino group wherein the substituent is an alkyl (C1-C3) group, (3) a group represented by the formula (4-a): --NHOR8-a (4-a) wherein R8-a represents a hydrogen atom or an alkyl (C1-C3) group or (4) a group represented by the formula (2-a): ##STR387## wherein (A) R5 is (a) an alkyl (C1-C4) group which is substituted with a mono- or di-alkyl-(C1-C3)-substituted aminocarbonyl group or carboxyl group or (b) a pyridyl group and R6 is a hydrogen atom or an alkyl (C1-C4) group, or (B) R5 and R6 jointly represent an alkylene chain to form, together with the adjacent nitrogen atom, (a) a substituted 3- to 7-membered cyclic amino group wherein the substituent is an alkyl (C1-C3) group, carbamoyl group, a carboxyl group, a mono- or di-alkyl-(C1-C3) substituted aminocarbonyl group or a hydroxyl group, (b) an unsubstituted 3- to 7-membered cyclic amino group which may contain double bond(s) in the ring thereof, or (c) ##STR388##|
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.